ea0073oc6.5 | Oral Communications 6: Calcium and Bone | ECE2021
Allas Soraya
, Ovize Michel
, Culler Michael D.
, Geraul Clarisse
, Jeroen van de Wetering
, Mannstadt Michael
Hypoparathyroidism is a rare disease characterized by a deficiency in parathyroid hormone (PTH) that results in hypocalcemia and hyperphosphatemia. Current treatment approaches, including high dose oral calcium and active vitamin D, as well as recombinant human PTH (1–84), do not provide adequate or consistent control of either serum calcium or clinical symptoms over a full 24-hour period. AZP-3601 is a novel 36 amino-acid PTH analog that has been designed to potently bi...